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MOTS-c 10mg

MOTS-c 10mg

$190.00Price
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MOTS-C is a mitochondrial-derived peptide composed of 16 amino acids encoded by the 12S rRNA region of the mitochondrial genome. Research demonstrates MOTS-C significantly enhances exercise performance, improves insulin sensitivity, and promotes metabolic homeostasis. In animal studies, MOTS-C has been shown to prevent diet-induced obesity, reduce fat accumulation, increase skeletal muscle glucose metabolism, and improve physical capacity in aging subjects. The peptide translocates to the nucleus during metabolic stress to regulate gene expression through AMPK pathway activation. Studies indicate MOTS-C increases exercise endurance by 12-15%, prevents muscle atrophy, and enhances mitochondrial function in skeletal muscle tissue.


Research Applications

Exercise Performance & Muscle Function

MOTS-C improves physical performance and muscle function by enhancing metabolism, activating AMPK/PGC-1α signaling, and regulating CK2. Exercise naturally increases its levels, and supplementation has been shown to boost endurance and running capacity in studies.

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Metabolic Health & Fat Loss

MOTS-C supports metabolic balance by improving insulin sensitivity, increasing glucose uptake, and promoting fat oxidation. Research shows it can prevent diet-induced obesity without reducing calorie intake and lowers inflammation linked to metabolic disease.

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Aging & Cellular Protection

Levels decline with age, but supplementation improves physical capacity and metabolic health in aging models. MOTS-C enhances mitochondrial function, reduces oxidative stress, and helps protect against age-related cellular damage.

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Cardiovascular Health & Tissue Repair

MOTS-C supports heart health by improving mitochondrial function and reducing oxidative stress. It also shows anti-inflammatory effects and may help protect tissues from damage in metabolic and liver-related conditions.

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Muscle Preservation

MOTS-C helps prevent muscle loss by reducing myostatin and supporting protein synthesis. It preserves lean muscle during metabolic stress and aging while improving endurance-related muscle adaptations.

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